Testosterone Enanthate: What Is It?

Testosterone enanthate is an “ester” of testosterone commonly prescribed for the treatment of low testosterone, a condition also known as hypogonadism, or more simply “low T.”

Testosterone replacement therapy is designed to bring your testosterone levels back into the normal range.

testosterone enanthate injection

Testosterone enanthate (TE) is a popular “ester” of testosterone with a half-life of 4.5 days. It is one of the most popular forms forms prescribed for age-related low T in men.

TE is administered via intramuscular injections. Your prescribed dosage of TE is based on your medical history, presenting symptoms, testosterone levels, and individual wellness goals. Dosages of this drug will usually range from 50 to 400 mg every 2 to 4 weeks. 250mg tends to be the most popular dose prescribed. In general, total doses above 400 mg per month are not required because of the relatively long half-life of testosterone enanthate.

What is Testosterone Enanthate Prescribed For?

TE is a form of prescription testosterone replacement therapy or TRT. It is often sold under the brand name Delatestryl®. In the brand name or generic form, TE is prescribed for men who do not make enough male hormones on their own.

Testosterone Enanthate may also be prescribed for adolescent males who are experiencing delayed puberty. It has also been used secondarily in women with advancing inoperable metastatic (skeletal) mammary cancer who are one to five years postmenopausal.

Testosterone Enanthate Dosage*

Like all forms of TRT, TE is prescribed as a “cycle.” A typical cycle of will be prescribed for six months of bi-monthly injections.

According to its prescribing information, the Testosterone Enanthate dosage and duration of therapy depend on age, sex, diagnosis, your particular response to treatment, and appearance of adverse effects.

In general, total doses above 400 mg per month are not required because of the prolonged action of the preparation. Injections more frequently than every two weeks are rarely indicated.

  • Dosing for male hypogonadism: for age-related low T, the suggested dosage is 50 to 400 mg every 2 to 4 weeks.
  • In males with delayed puberty: Various dosage regimens have been used; some call for lower dosages initially with gradual increases as puberty progresses, with or without a decrease in maintenance levels. Other regimens call for higher dosage to induce pubertal changes and lower dosage for maintenance after puberty. The chronological and skeletal ages must be considered in determining the initial dose and adjusting the dose.
  • Dosage for palliation of inoperable mammary cancer in women: A dosage of 200 to 400 mg every 2 to 4 weeks is recommended. Women with metastatic breast carcinoma must be followed closely because androgen therapy occasionally appears to accelerate the disease.

Administration

How to Use Testosterone Enanthate

TE is for intramuscular use only. Before administering this medication , you are advised to check this product visually for particles or discoloration. If either is present, do not use the liquid.

testosterone injection

When properly given, injections of TE tend to be well tolerated. Care should be taken to slowly inject the preparation deeply into the gluteal muscle, being sure to follow the usual precautions for intramuscular administration, such as avoiding injection into a vein.

You will be shown exactly how to administer your TE injections. Do not self-inject this medicine if you do not fully understand how to give the injection and properly dispose of used needles and syringes.

Please see your medication’s insert or check with your doctor or healthcare provider for more specific instructions on how to administer your particular prescription of this medication.

Testosterone Enanthate Benefits

Specific Testosterone Enanthate benefits for men diagnosed with low T include:

  • Increased energy.
  • Improved libido and reduced symptoms of erectile dysfunction.
  • Weight loss.
  • Improved bone density and bone development.
  • Decreased risk of coronary artery disease.
  • Increases exercise capacity.
  • Increased ability to build lean muscle.
  • Improved moods.
  • Improved cognition.

How Does Testosterone Enanthate Work?

Testosterone Enanthate works by increasing testosterone levels by making up for the hormone your body is failing to produce on its own. By administering TE to men with low testosterone levels, the medication effectively replenishes the hormone in their bloodstream and alleviates symptoms associated with low T, such as decreased libido, fatigue, muscle loss, and mood swings, by restoring their hormone levels to within a normal range.

Testosterone Enanthate Side Effects

According to the prescribing information for TE, there are some warnings and contraindications that users need to be aware of.

Interactions

According to the Prescribing Information, this medication should not be used:

  • In patients with a known hypersensitivity or have had allergic reactions to the drug
  • In patients with a history of cardiovascular disease or related medical conditions.
  • In males with carcinoma of the breast
  • In males with known or suspected carcinoma of the prostate gland
  • In women who are pregnant or may become pregnant
  • In patients with serious hepatic (liver) or renal (kidney) disease
  • This drug may interact with other medications. Tell your prescriber about any medications you may be taking, even herbal products.

Warnings

Before accepting a prescription for TE, tell your doctor if:

  • You are allergic to TE or any other part of the TE injection.
  • You are male and have breast or prostate cancer.
  • You have any health problems: heart, kidney, or liver disease.
  • You are pregnant or may be pregnant.
  • You are breastfeeding. Do not breastfeed while you take TE injections.
  • Women should be observed for signs of virilization (deepening of the voice, hirsutism, acne, clitoromegaly, and menstrual irregularities)

In addition, tell your healthcare provider about any medicines you are taking, including prescription and over-the-counter medicines, vitamins, and herbal supplements. TE may affect how other medicines work, and other medicines may affect how well TE works.

See your medication’s insert for a complete list of potential drug interactions and other warnings regarding the use of this medication.

TE injections are approved for the treatment of hypogonadism and are generally regarded as safe. However, like any prescription medication, TE has some potential side effects.

Common Side Effects of Testosterone Enanthate

  • Nausea
  • Vomiting
  • Headache
  • Skin color changes
  • Oily skin
  • Hair loss
  • Acne may occur
  • Pain and/or swelling at the injection site

Less Frequent Testosterone Enanthate Side Effects

  • High Amount Of Calcium In The Blood
  • High Blood Pressure
  • Enlarged Prostate
  • Inflammation Of The Epididymis Of The Testicles
  • Dizziness
  • Shortness of breath
  • Sleep Apnea
  • Low Energy
  • Loss of appetite
  • Visible Water Retention
  • Temporary Redness Of Face And Neck
  • Raised Prostate Specific Antigen

Rare Testosterone Enanthate Side Effects

  • Liver Cancer
  • Low Levels Of White Blood Cells
  • Suicidal Thoughts
  • A Heart Attack
  • A Clot In The Lung
  • Heart Failure
  • A Stroke
  • Blood Clot In A Deep Vein Of The Extremities
  • Blood Clot Formation In Vein
  • Acute Respiratory Distress Syndrome, A Type Of Lung Disorder
  • Liver Tissue Death
  • Damage To The Liver And Inflammation
  • Microscopic Blood-Filled Cavities In The Liver
  • Inflammation Of The Liver With Stoppage Of Bile Flow
  • A Yellowing Of The Eyes Or Skin From the Buildup Of Bilirubin Called Jaundice
  • Abnormal Increase In Red Blood Cells
  • High Cholesterol
  • Depression
  • Aggressive Behavior
  • Feelings Of Hostility
  • Low Sperm Count
  • Decreased Appetite
  • Irritability

See your medication’s insert or the Prescribing Information for a complete list of potential side effects.

Your prescription for this medication will be tailored to meet your goals and lifestyle. You will be carefully monitored throughout the cycle of TRT, so any chance of side effects should be kept to a minimum. Tell your doctor if you are experiencing any of these or other side effects while taking this medication.

How Does Testosterone Enanthate Compare to Other Forms of Testosterone

Three esters of testosterone are most commonly prescribed for TRT: Testosterone Enanthate, Testosterone Cypionate, and Propionate. They are all the same medication but differ somewhat in the molecular structure, impacting their “half-lives.” A drug’s half-life indicates how quickly it takes effect and how long it lasts. The three types also differ a bit it price and available doses.

Here is a chart that compares the three.

Comparison Enanthate Cypionate Propionate
Effectiveness High High High
Side Effects Mild to Moderate Mild to Moderate Moderate (More frequent injections)
Half-Life 5-10 days 7-12 days 2-3 days
Price $$ $$ $
Dosages Available 50-250 mg/mL 100-200 mg/mL 50-100 mg/mL
How Administered Injection Injection Injection
Brand Names Delatestryl, Xyosted Depo-Testosterone Testoviron, Viromone

How to Buy Testosterone Enanthate in the US

You cannot buy TE or any other esters in the US without a doctor’s prescription. Doing so is not only against the law but can be extremely dangerous to your health and well-being. Using TE without a doctor’s prescription increases the risks of side effects or adverse reactions. Using any form of TRT illegally can result in severe complications, even death.

We can take you through the process of getting a legitimate prescription for TE. Click this link to get started.

testosterone injection for sale

Can You Buy Testosterone Enanthate Online

You can buy TE online, but only from a legitimate online seller of TRT injections like Nexel Medical. Such sellers like Nexel have been fully vetted and approved to sell prescription hormone products online. Getting a prescription from Nexel Medical for TE is not hard. It only takes these few steps.

  • Step 1 – Fill out our online medical history form.
  • Step 2 – Initial consults with one of our healthcare professionals. This initial consult could possibly be done via a telemedicine visit.
  • Step 3 – After your initial consultation, if we suspect you could benefit from a prescription for TE, our healthcare team will refer you to a lab to have your testosterone levels tested.
  • Step 4 – If your lab tests indicate low T, you will be prescribed a cycle of TE injections.
  • Step 5 – We will take you through filling your prescription, and your prescribed injection kit will be delivered.

How to Get the Best Price on Testosterone Enanthate?

If you have questions about the cost of TE, please contact us. However, rather than wondering where to get the best price on TE, you should consider where to get the best treatment for low T. At Nexel, we believe our price for TE is competitive. You may find some online prescribers who sell TE for less and some who charge more. You should not decide where to get online TRT on price alone. An old adage says you “get what you pay for.” You should choose where to get your TRT by selecting the cheapest clinic. You want to work with a clinic like ours that has years of experience in understanding the subtle nuances of prescribing hormone replacement therapy for men. At Nexel, our doctors and technicians specialize in treating age-related hormone loss in men. We look at you as a whole and customize your TRT to your exact needs, fitness goals, and lifestyle.

Frequently Asked Questions About Testosterone Enanthate Injections

What is Testosterone Enanthate, and what is it used for?

TE is a long-acting ester of testosterone, primarily used to treat low testosterone levels (hypogonadism) in men. It helps restore normal testosterone levels, improving energy, mood, libido, and muscle mass. It’s also used in hormone therapy for transgender men and sometimes in bodybuilding.

How quickly does Testosterone Enanthate take to work?

TE generally starts working within 3 to 4 weeks. Users may notice initial improvements in energy, mood, and libido during this time. Muscle growth and strength gains typically become noticeable after 6 to 8 weeks. Full benefits can take several months to manifest.

How is Testosterone Enanthate administered?

Testosterone Enanthate is injected intramuscularly, often into the glute or thigh muscle. Injections are typically given every 1 to 4 weeks, depending on dosage and individual needs. The slow-release nature of this ester ensures prolonged effects over time.

Are there alternatives to Testosterone Enanthate for injections?

Yes, several injectable testosterone esters serve as alternatives to Testosterone Enanthate:

  • Testosterone Cypionate – Similar to Enanthate, but with a slightly longer half-life, requiring injections every 7 to 14 days. It’s widely used in the US.
  • Testosterone Propionate – A shorter-acting ester that requires more frequent injections (every 2 to 3 days). It provides faster results but may cause more injection site discomfort.
  • Testosterone Undecanoate – A long-acting ester, often injected every 10 to 12 weeks. It’s used for sustained testosterone levels with fewer injections.
  • Sustanon 250 – A blend of four testosterone esters (including propionate and decanoate) that provide both immediate and long-lasting effects, injected every 3 to 4 weeks.

Each ester differs in release time and injection frequency, so the choice depends on personal preferences and treatment goals.

Patient Testimonials

“Before starting testosterone replacement, I felt like I was constantly running on empty. I had no energy, my workouts weren’t yielding results, and my mood swings were affecting my family life. After just a few months on testosterone enanthate therapy, I noticed a complete turnaround. I feel stronger, sharper, and more motivated than I have in years. I can’t thank the team at Nexel enough for giving me my life back.” — Mark R., 42

“I was skeptical about TRT at first, but the staff at Nexel took the time to explain everything and monitor my progress carefully. The results have been incredible. My libido is back, I’ve lost weight, and I finally feel like myself again. I even sleep better now. It’s been a life-changing experience, and I recommend TE shots to any guy who feels like age is slowing him down.” — James L., 55

“I didn’t realize how much low testosterone was affecting me until I started TRT. I assumed fatigue and brain fog were just part of being on the plus side of 35! Within weeks of starting TE treatment, I felt more energetic, focused, and confident. It’s amazing how something so simple can have such a big impact. The clinic staff made the whole process easy and professional. I wish I had done this sooner!” – Jose G., 38

Take the first step to renewed strength and vitality! Contact Us today and see if you qualify for a prescription for the life-changing benefits of TRT.

*Dosing information is provided for informational purposes only and should not be construed as instructions for use. Consult your physician or pharmacist for guidance regarding your dose of Testosterone Enanthate.

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