Testosterone Enanthate Injections Side Effects

Testosterone enanthate is a commonly prescribed "ester" of testosterone. Testosterone enanthate is approved by the FDA for the treatment of testosterone deficiencies. It is generally regarded as safe; however, like any prescription medication, testosterone enanthate has some potential side effects.  

Testosterone enanthate is a prescription medication. It is administered via intramuscular injections. Your prescribed dosage of testosterone enanthate is based on your medical history, presenting symptoms, testosterone levels, and your individual wellness goals.

Testosterone Enanthate Indications and Contraindications

The most commonly prescribed brand names of testosterone enanthate include Delatestryl and Xyosted. You may also be prescribed one of the generic versions of testosterone enanthate injections made by Watson and West-Ward pharmaceuticals.

Indications for Testosterone Enanthate

In the brand name or generic form, testosterone enanthate is indicated for the treatment of men who do not make enough testosterone on their own — a condition known as hypogonadism. It is a derivative of the primary endogenous androgen testosterone, designed for intramuscular administration.

Testosterone Enanthate may also be prescribed for adolescent males who are experiencing delayed puberty. It has also been used secondarily in women with advancing inoperable metastatic (skeletal) mammary cancer who are one to five years postmenopausal.

Warnings and Contraindications for Testosterone Enanthate

According to the prescribing information of all brands of testosterone enanthate, there are some warnings and contraindications that users need to be aware of.

Interactions

According to the Prescribing Information, Testosterone Enanthate should not be used:

• In patients with a known hypersensitivity or allergy to the drug
• In patients with a history of cardiovascular disease
• In males with carcinoma of the breast
• In males with known or suspected carcinoma of the prostate gland
• In women who are pregnant or may become pregnant
• In patients with serious hepatic (liver) or renal (kidney) disease

Warnings

Before accepting a prescription for Testosterone Enanthate, tell your doctor if:

• You have an allergy to testosterone or any other part of testosterone enanthate injection.
• You are male and have breast or prostate cancer.
• You have any of these health problems: heart disease, kidney disease, or liver disease.
• You are pregnant or may be pregnant. Do not take testosterone enanthate injection if you are pregnant.
• You are breastfeeding. Do not breastfeed while you take testosterone enanthate injection.
• Women should be observed for signs of virilization (deepening of the voice, hirsutism, acne, clitoromegaly, and menstrual irregularities)

In addition, tell your healthcare provider about any medicines you are taking, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Testosterone Enanthate may affect how other medicines work, and other medicines may affect how Testosterone Enanthate works.

See your medication’s insert for a complete list of potential drug interactions and other warnings regarding the use of Testosterone Enanthate.

Testosterone enanthate is commonly prescribed for patients diagnosed with testosterone deficiency. 

Testosterone Enanthate Side Effects

Testosterone enanthate injections are FDA-approved for the treatment of hypogonadism (low testosterone) and are generally regarded as safe. However, like any prescription medication, Testosterone enanthate injections have some potential side effects.

Common Side Effects of Testosterone Enanthate

• Nausea
• Vomiting
• Headache
• Skin color changes
• Oily skin
• Hair loss
• Acne may occur
• Pain and/or swelling at the injection site 

Less Frequent Side Effects of Testosterone Enanthate

• Cancer Of The Prostate Gland
• High Amount Of Calcium In The Blood
• High Blood Pressure
• Enlarged Prostate
• Inflammation Of The Epididymis Of The Testicles
• Dizziness
• Sleep Apnea
• Low Energy
• Visible Water Retention
• Temporary Redness Of Face And Neck
• Raised Prostate Specific Antigen

Rare Side Effects of Testosterone Enanthate

• Liver Cancer
• Low Levels Of White Blood Cells
• Suicidal Thoughts
• A Heart Attack
• A Clot In The Lung
• Heart Failure
• A Stroke
• Blood Clot In A Deep Vein Of The Extremities
• Blood Clot Formation In Vein
• Acute Respiratory Distress Syndrome, A Type Of Lung Disorder
• Liver Tissue Death
• Damage To The Liver And Inflammation
• Microscopic Blood-Filled Cavities In The Liver
• Inflammation Of The Liver With Stoppage Of Bile Flow
• A Yellowing Of The Eyes Or Skin From Buildup Of Bilirubin Called Jaundice
• Abnormal Increase In Red Blood Cells
• High Cholesterol
• Depression
• Aggressive Behavior
• Feelings Of Hostility
• Low Sperm Count
• Decreased Appetite
• Irritability

See your medication’s insert or the Prescribing Information for a complete list of potential side effects.

Your prescription for Testosterone Enanthate will be tailored to best meet your particular goals and lifestyle. You will be carefully monitored over the course of your treatment with Testosterone Enanthate, so any chance of side effects should be kept to a minimum. Tell your doctor if you are experiencing any of these or other side effects while taking Testosterone Enanthate.

Why Do These Side Effects of Testosterone Injections Occur?

In practically every circumstance that someone experiences side effects from testosterone enanthate injections, it is because they are using testosterone enanthate illegally without a legitimate doctor’s prescription or in a manner other than the way it has been prescribed for them.

Any drug, even common over-the-counter medications such as aspirin or cold remedies, has a long list of possible side effects. Some of the listed side effects of testosterone enanthate occur because different people have different tolerances to any given medication.

You can take a drug, even one that has been prescribed for you, and have some negative reactions, whereas even someone as close to you as a brother or sister can take the exact same medication and experience little or no issues or side effects.

That is exactly why drugs like testosterone enanthate must list all of their potential side effects.

Anyone can have anything on the list. It certainly does not mean that everyone will.

As with any prescription drug or medical procedure, testosterone enanthate can have some side effects.

 What is the Prescribed *Dosage of Testosterone Enanthate?

Testosterone Enanthate is available in injectable liquid form in 5 mL (200 mg/mL) multiple-dose vials. Each mL of sterile, colorless to pale yellow solution provides 200 mg Testosterone Enanthate in sesame oil with 5 mg chlorobutanol (chloral derivative) as a preservative. According to the complete prescribing information for Delatestryl/testosterone enanthate, *dosage and duration of therapy will depend on age, sex, diagnosis, patient’s response to treatment, and appearance of adverse effects.

In general, total doses above 400 mg per month are not required because of the prolonged action of the preparation. Injections more frequently than every two weeks are rarely indicated.

• Dosing for male hypogonadism: As replacement therapy, i.e., for eunuchism, the suggested dosage is 50 to 400 mg every 2 to 4 weeks.
• In males with delayed puberty: Various dosage regimens have been used; some call for lower dosages initially with gradual increases as puberty progresses, with or without a decrease to maintenance levels. Other regimens call for higher dosages to induce pubertal changes and lower dosages for maintenance after puberty. The chronological and skeletal ages must be taken into consideration, both in determining the initial dose and in adjusting the dose.
• Dosage for palliation of inoperable mammary cancer in women: A dosage of 200 to 400 mg every 2 to 4 weeks is recommended. Women with metastatic breast carcinoma must be followed closely because androgen therapy occasionally appears to accelerate the disease.

How to Avoid Any Possible Negative Effects of Testosterone Enanthate

You can avoid most of the side effects of testosterone therapy by working with a reputable doctor. Like the treatment you receive for any serious medical treatment, the doctor you choose to provide your therapy is instrumental in the outcome of your recovery.

If you get your prescription for testosterone from a skilled and experienced provider of testosterone therapy, you will likely have a very good experience and have very few, if any, side effects from your testosterone replacement treatments.

You should only work with a testosterone doctor or testosterone clinic that has a proven track record for safety. You should look for a provider of testosterone therapy that is known to carefully monitor their patients and who treats every case as an individual.

Furthermore, to minimize any potential side effects of testosterone therapy, it is essential that you follow all of your doctor’s instructions. Never exceed your recommended dose. Only take the number of injections you have been prescribed per week. If you do experience any side effects, they can usually be fixed by simply adjusting your dose of testosterone.

Patients with low testosterone should not let the possible side effects of testosterone therapy deter them from using testosterone enanthate if your doctor recommends it.

Now that you know a little bit more about free testosterone enanthate injections, why not take a minute to contact us and learn more about how testosterone replacement therapy can improve your quality of life.

*Dosing information is provided for informational purposes only and should not be construed as any kind of instructions for use. Consult your physician or pharmacist for guidance regarding your particular dose of Testosterone Enanthate.