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Whenever people want to know what the difference is between one thing and another, it usually turns out that it’s a good thing they asked. The question of what is the difference between testosterone cypionate and testosterone enanthate is often asked by people who are under the assumption that these two substances are so similar that the minor differences between them don’t really matter – but they do. And as Low T treatment options, those difference could matter to you if you are considering using doctor prescribed testosterone replacement therapy (TRT).
Both of these controlled substances are pharmaceutically manufactured versions of bio-similar male androgen and are used to increase clinically insufficient testosterone levels. They are both classified as slow-acting testosterone esters with a release time of between 10 to 14 days. One version (cypionate) is suspended in cottonseed oil and has an 8-carbon ester chain, while the other (enanthate) is suspended in sesame oil and has a 7-carbon ester chain. But while they are widely considered to be interchangeable for medical use, some patients have strong preferences about using one form instead of the other because of the slightly different characteristics of each.
Cypionate, which tends to be the more commonly form that US doctors prescribe, has a longer active life (due to its slightly slower release time) than enanthate and subsequently requires fewer injections over the course of a patient’s treatment cycle. That is often a meaningful factor to adults who want to know what is the difference between testosterone cypionate and enanthate treatments. For some patients, a price difference between the two types would be a meaningful factor; but these two prescription medications typically don’t vary much in terms of their usage costs.
So what it usually comes down to is the form of treatment that a patient’s TRT doctor prescribes, presumably after being made aware of any preference that the patient might have. At Nexel Medical, we do our best to accommodate the treatment preferences of every patient we treat for Low T; and whenever our doctors have legitimate medical reasons for recommending one form of injectable testosterone over another, we make certain that our patients understand why we believe it is their best option for effective treatment.
Some of the adults who are focused on finding out what is the difference between testosterone cypionate and enanthate don’t realize that there are other things to find out about that can make a difference in regard to their male hormone supply. One of these things is learning about an estrogen known as estradiol, which is typically identified on blood tests as E2. But what does it have to do with your body’s testosterone levels? As it turns out, estradiol has a very strong influence on the status of your male hormone levels and there are certain factors that can increase the amount of estradiol your body produces. The bottom line is that the more estradiol you have, the less available testosterone you will have.
What E2 does that is so self-defeating to your male hormone supply is it binds to your body’s androgen receptors thereby causing them to become useless; this makes it a testosterone receptor antagonist. It also causes your body to produce fewer androgen receptors as time goes on; and if it successfully binds to your estrogen receptors, it activates them. As a result of your higher estrogen levels, you can find yourself developing excess belly fat; “man boobs”; and prostate enlargement. And using TRT alone may not be enough to reverse the situation, because the supplemental testosterone it supplies needs androgen receptors to bind to and your endocrine system might not have enough of these, all due to its production of estradiol, which has been facilitated by the presence of the aromatase enzyme in your body. Knowing what is the difference between testosterone cypionate and enanthate is not going to matter much to you under these physiological circumstances.
However, aromatase inhibitors can be used to bind to your body’s aromatase enzymes and prevent them from converting your testosterone to estradiol. So some TRT patients will need to use an AI (aromatase inhibitor) in order for their treatment to be truly effect and produce the results they want. Don’t forget to discuss this with your therapy’s prescribing physician because it could have a much greater impact on your results than whether you end up using either testosterone cypionate or testosterone enanthate. In fact, it is always an excellent idea to make a list of all of the questions you have about using TRT before you contact a hormone replacement therapy doctor or clinic about using treatment for your low T symptoms.
Perhaps you’ve come to realize that there could be other important aspects surrounding the use of testosterone replacement therapy that you could be unaware of; or maybe you would like the opportunity to discuss what is the difference between testosterone cypionate and enanthate with a medical professional in greater detail. At Nexel Medical, our doctors believe that the more adults understand about how the various forms of TRT work – and what can prevent them from working – the more successful their treatment will be.
So Nexel Medical has always been committed to providing comprehensive and up-to-date information about all aspects of using male hormone replacement therapy to any adult who wants to become more educated about it. When our doctors decided to make our TRT programs available to adults across the US, we also decided to make accurate and helpful information about their Low T treatment options universally available to US adults, as well. And we provide this information, without obligation of any kind, to all adults who contact us. It doesn’t matter what the questions on your list are; if there is something that you want to learn about using any form of testosterone replacement therapy, our clinical advisors are always glad to answer all of them and discuss any of your personal concerns about using Low T replacement therapy.
And if you have ever thought what is the difference where you get your information on TRT from, let us assure that it can make a significant difference. Only experienced and qualified hormone therapy medical providers like Nexel Medical can comprehensively answer highly specific questions such as what is the difference between testosterone cypionate and enanthate and explain why that matters to you. If you have every unsuccessfully attempted to have a detailed discussion about using TRT with your primary care provider, then you have already learned it wasn’t the way to get the answers you were looking for.
Life is too short to waste time looking for answers to questions about how to stay healthy and vital; so if you want to save yourself time and frustration in getting information about eliminating your Low T symptoms, just call us at Nexel Medical. We will give you all the time you need to get your questions answered – and we can also help you to get your TRT program underway.
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