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There are several different types of testosterone medications that are prescribed to treat testosterone deficiency.
Testosterone replacement therapy is the standard of care for treating patients with low testosterone. The most common cause of low testosterone is age-related testosterone loss.
Testosterone levels steadily increase throughout a male’s life as he grows from a boy to a man. Testosterone peaks for most men around the age of twenty, and then testosterone levels start to drop steadily. Once a man is over 35, he can expect his testosterone levels to drop by about 1% to 2% per year.
Signs that you may require prescription medication for low testosterone, also known as “hypogonadism," include:
Prescription testosterone medication is available in several forms. You can take prescription testosterone therapy via:
You and your doctor will decide which delivery method is best for you based on your testosterone test results, your medical history, and individual needs and lifestyle.
Our doctors have found that testosterone injections are the most effective method to deliver testosterone replacement. There are several reasons why we believe that testosterone injections are the best medication for low testosterone.
As opposed to other forms of testosterone medications such as gels, creams, or patches:
Testosterone injections are more effective at delivering testosterone because it is injected right into your bloodstream.
With testosterone injections, there is no chance of "cross-contamination" and transfer to another person via skin or clothing contact. That kind of cross-contamination by others coming into contact with topical testosterone can have severe side effects, especially for children or pregnant women. Topical testosterone is never recommended for men who are living in a household with children.
There is such a variety of types and dosages available in testosterone injections that your doctor is bound to find one that is best for your symptoms and lifestyle. And should your dosage of testosterone need to be adjusted over the course of your therapy, that is also very easy with injections. The dosages available in other forms of testosterone medications are far more limited.
If you and your doctor decide that testosterone injections are best for you, you will be shown how to safely and painlessly give yourself your testosterone injections.
Injectable testosterone that is prescribed for testosterone replacement therapy is available in several forms and sold under a variety of brand names. Injectable testosterone is usually prescribed as testosterone enanthate, testosterone cypionate, or testosterone propionate. All are what are known as testosterone esters. Esterification is a chemical process that makes testosterone more soluble and therefore injectable.
The following information on dosages and indications comes from the prescribing information relative to each of the forms.
Testosterone Cypionate is a form of prescription testosterone replacement therapy. It is also often sold under the brand name DEPO-Testosterone, which is manufactured by Pfizer. In the brand name or generic form, Testosterone Cypionate is prescribed for men who do not make enough testosterone on their own — a condition known as hypogonadism.
In males, testosterone is responsible for many normal functions, including the growth and development of the genitals, muscles, and bones. It also helps cause normal sexual development (puberty) in boys. Testosterone belongs to a class of drugs known as androgens. Testosterone Cypionate works by affecting many body systems so that the body can develop and function normally.
Dosage Forms and Strengths Available of Testosterone Cypionate
Testosterone Cypionate is available as an injectable solution given into the muscle. Testosterone cypionate is a self-injectable drug. Testosterone cypionate is a white or creamy white crystalline powder, odorless or nearly so and stable in the air. It is insoluble in water, freely soluble in alcohol, chloroform, dioxane, ether, and soluble in vegetable oils. The brand name, DEPO-Testosterone, is available in two strengths, 100 mg/mL and 200 mg/mL testosterone cypionate.
Each mL of the 100 mg/mL solution contains:
Each mL of the 200 mg/mL solution contains:
Testosterone Enanthate is a form of prescription testosterone replacement therapy. It is also often sold under the brand name Delatestryl®. In the brand name or generic form, Testosterone Enanthate is prescribed for men who do not make enough testosterone on their own — a condition known as hypogonadism. It is a derivative of the primary endogenous androgen testosterone, designed for intramuscular administration.
Testosterone Enanthate may also be prescribed for adolescent males who are experiencing delayed puberty. It has also been used secondarily in women with advancing inoperable metastatic (skeletal) mammary cancer who are one to five years postmenopausal.
Dosage Forms and Strengths Available
Testosterone Propionate is an injectable form of prescription testosterone replacement therapy. Testosterone Propionate is a slower releasing anabolic steroid with a short half-life. It is the shortest-estered testosterone steroid. This characteristic allows the user to run short testosterone propionate cycles of 8-10 weeks.
Testosterone Propionate is prescribed for male androgen deficiency, also known as andropause, hypogonadism, low testosterone, or low-T. It can also be prescribed for adolescent boys with delayed onset of puberty and to treat certain types of breast cancer in women.
Dosage Forms and Strengths Available
Testosterone Propionate is a short-acting oil-based injectable formulation of testosterone. The most common dosage for Testosterone Propionate is:
All of the types of prescription testosterone medications listed above basically have the same benefits and potential side effects.
Benefits
Testosterone cypionate works to treat hypogonadism (low testosterone) in males by replacing the testosterone your body is unable to make. Testosterone cypionate belongs to a class of drugs called androgens. Testosterone Cypionate injections have been shown to treat and/or improve many of the symptoms of low testosterone, such as:
Side Effects
More common – Some of the more common side effects of Testosterone Cypionate include:
Less common – Some of the potentially severe, though less common side effects of Testosterone Cypionate include:
See your specific testosterone medication’s insert or the prescribing information for a complete list of potential side effects.
Testosterone injections are prescribed as different esters of testosterone. Esters are all the same drug; they are simply different versions of testosterone. The different types of esters of testosterone differ only in:
The chart below compares the average prices of the most commonly prescribed esters of testosterone.
| Type of Testosterone | Dosage | Cost |
| Depo-Testosterone | 10ml of 200 mg/ml | $300.00 |
| Depo-Testosterone | 1ml of 200 mg/ml | $70.00 |
| Depo-Testosterone | 100mg/mL 10mL | $300.00 |
| Watson Testosterone Cypionate | 10ml of 200mg/ml | $275.00 |
| Testosterone Cypionate | 20mg/mL 5mL Vial | $175.00 |
| Testosterone Propionate | 100 mg/ml (10ml) | $200.00 |
The prices listed on the chart above are to be considered a guideline, you could pay a little more, or you could pay a little less, depending on the doctor or clinic prescribing your testosterone medication.
If you are shopping around for testosterone therapy, the price of your testosterone injections is a factor. However, the price that you might pay for your testosterone injections should not be the deciding factor on the testosterone clinic or testosterone doctor you choose. Do not cut corners and possibly compromise your health by going to the clinic that advertises the lowest prices on testosterone shots. Remember, as in any other purchase – you get what you pay for.
When shopping for testosterone therapy, you should be more concerned about your prescriber’s skills and experience than the price you will pay for your testosterone injections, and use the prices listed above as your guide.
Now that you know more about the different kinds of testosterone medications, why not take a minute to contact us and learn more about how testosterone replacement therapy can improve your quality of life.
*Any dosing information on this page is provided for informational purposes only and should not be construed as any kind of instructions for use. Consult your physician or pharmacist for guidance regarding your particular dose of testosterone medication.
Sources:
https://www.pfizer.com/products/product-detail/depo_testosterone
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